Karen shares her IVF journey

IVF Patient Journey- Karen

Karen shares her IVF journey

“I took time to educate myself about the IVF process. I started following some fertility accounts on Instagram and realized how big this community is. It’s the worst club to be a part of, but it has the best members!”

Today we are excited to introduce a new type of patient story to you. We will be sharing Karen’s journey and her efforts to become a mother. Karen had no reason to suspect she would have trouble conceiving until she tried for almost a year with no success. Now she is preparing to go through IVF and is ready to share the good, bad and the emotional with you. It is important to remember that each patient case is unique and Dr. Miller personalizes each treatment plan based on the patient’s age, medical history and test results. Here is Karen’s story:

 My name is Karen and I am 38 years old, I have been married to my husband for four years and we live in Lombard with our sweet 5-year-old boxer mix, Cali. When my husband and I started trying for a family in 2021 and it wasn’t happening as quickly as I thought, I got worried. We both live a very healthy lifestyle, have clean bills of health and never thought we would have any issues trying to conceive. I had a ton of girlfriends that got pregnant very quickly, but then I also had several that went through IVF or were currently going through it. I didn’t know much about IVF because I tried not to let my mind think that would ever be an option for us. But then reality started to hit me. After eight months of no success, we decided that we needed to look into the IVF process and find a doctor.

 

I found Dr. Miller by doing some research on local doctors online through RE doctor websites. My friends who went through IVF all had different stories and different outcomes, with doctors all over the suburbs. My main concern was finding a clinic that didn’t make me feel like just a number. I wanted a doctor that had years of experience, would take the time to understand what we were going through and not push us through the consultation process. I also wanted to make sure there was a supportive nursing team that would be there for us during our journey. After our first meeting with Dr. Miller, I said to my husband, “Wow, this man is going to help get us our baby, I like him!”

After all the bloodwork, baseline ultrasound, HSN and semen analysis, we found out that my husband and I are both factors. Obviously my age was a huge factor and my husband had abnormal morphology, which made Dr. Miller suggest that we should go straight to IVF with ICSI (a method that involves injecting sperm directly into an egg to induce fertilization and pregnancy).

Actually hearing those words brought me to tears after we got off the call. I couldn’t believe we were going to have to go through this. A ton of questions went through my mind of why can’t I just be like everyone else, why can’t this be easy for us? I took time to educate myself about the IVF process. I started following some fertility accounts on Instagram and realized how big this community is. It’s the worst club to be a part of, but it has the best members! Finding girls that are currently going through the exact same process is a blessing. They totally know what you are going through and they feel your pains, the struggles and the wins.

Fast forward to October of 2022, and we were ready for our first round for egg retrieval. I started stims and was on a very basic protocol- menopur, follistim, ganirelix and double trigger shot. Once I got that big box of meds delivered, I was a little overwhelmed. Organizing, setting up my area where I was going to do the shots and going through the consultation with Nurse Patty, gave me the confidence that I was ready to take on the shots. I watched a ton of videos online of girls that were going through stims on Instagram to hype me up.

I had talked about the shots with my husband and showed him videos to get him ready for what I was going to be doing. I asked him (even though I knew I was going to be giving myself the shots) if he wanted to give me the shots and he said he would do them if I didn’t think I could. I let him know that he was off the hook with the stim shots, but that he would have to step up to give me the PIO shots once we got to that point in our journey.

To be honest, the shots were not that bad. Mixing and getting the shots prepped is the most hassle. I usually put on some music to sing along to as I am doing the shots to take my mind off what is going on!

I did ten days of shots and had my egg retrieval on November 3. I got six eggs! It was one more than I thought I was going to get. Results came the next day, that four matured and two fertilized with ICSI. Then we waited six more days to hear how those two did. On day 6, we received a message that only one made it to blast and a biopsy was being sent off for PGT-A testing.

We went through another long  two week wait. I received the result that our only embryo was low mosaic- trisomy 1. It was heartbreaking to hear that our only embryo from our first egg retrieval had these results. We didn’t really understand what this meant, so we scheduled a follow up call with Igenomix with a genetic counselor to review the results. I am so glad we did, because after finding out what low mosaic really meant, we decided that we indeed were going to keep this embryo frozen. There might be some hope with this little embaby. After processing all this news, we knew that we had to get right back into another egg retrieval. When we first started this process, we were prepared with the possibility that we were going to have to do multiple egg retrievals based off of my test results.

At the end of November, we had our follow up consultation with Dr. Miller to review what happened and get his thoughts. He told us that this next round was going to be different and we are going to switch up the protocol now that we know what worked and what didn’t work. He gave us so much hope during that call, making sure to remind us that we are going to get our baby!  Since I knew we would be starting the process again sometime in January, my husband and I just took the time to enjoy the holidays and not focus on IVF. It was a nice distraction.

Heading into round 2, I am excited and nervous. I am looking forward to seeing the end results with this retrieval since we are switching up my protocol. Even though I have been through this process once and I know what to expect, I have a feeling this path will be different and that’s ok. The main thing is that I have my support group to cheer me on, sending me positive vibes and prayers. Here we go round 2!

Stay tuned to follow Karen’s journey as she prepares for her second egg retrieval . She is excited to share her story with you and shed some light into the IVF process.


Patient Story- Lauren

Lauren celebrates her baby's first Christmas after IVF

“Now, I look at my daughter and have to pinch myself. I can’t believe she’s here!”

We know the holidays can be a challenging time for many of our patients. However, today we want to share Lauren’s story with you. This time last year, Lauren wondered if she would ever become a mother. Today, she has a beautiful baby girl. Unhappy with her previous clinic, Lauren came to Dr. Miller. He listened to her concerns and together they came up with a treatment plan. Another example of how important it is to advocate for yourself when it comes to your health. 

Lauren writes:

My story is one of finding hope with Dr. Miller and with the wonderful staff at the Advanced IVF Institute. My husband and I had been through a lot by the time I made a teary phone call to the receptionist (or angel?) at Dr. Miller’s office. We had been years-long patients elsewhere, and had experienced four failed IUIs and two rounds of IVF yielding only one embryo and subsequent miscarriage. We were tired, sad, and wondering if becoming parents was achievable. Our previous doctor told us we would be “lucky” to end up with one child, and suggested egg donation. After researching different fertility specialists online and comparing SART statistics, I knew Dr. Miller would be the best choice for us.

When we met with Dr. Miller, he had a thorough knowledge of our history, a plan, and compassion for what we had been through. I have PCOS and thyroid disease and felt that my previous clinic did not take this into account when creating my treatment plan.

Dr. Miller took my concerns seriously and addressed them. I had concerns about insulin resistance, he investigated it and treated it. I had concerns that my previous clinic did not take my thyroid disease seriously enough and allow for appropriate monitoring, he agreed and made sure my levels were optimal before proceeding. My husband was concerned about his inconsistent fertility testing, Dr. Miller confirmed that we were dealing with an element of male factor infertility.

After our first meeting, I distinctly remember him saying, “I might not get it the first time around, but I’m confident we will get you on the right treatment plan.” Well, he did get it the first time around. Imagine our surprise and delight when on our first round with Dr. Miller we ended up with five beautiful embryos, and a pregnancy on our first transfer. He and his staff celebrated with me each week when things were going well in my early pregnancy, and by the time I “graduated” these people felt like family.

Today, we have a beautiful baby. When recovering in the hospital, my husband asked me if I thought Dr. Miller knew how much he changed our lives. When we had no hope left, he gave us everything. I think about this time last year, and not in my wildest dreams did I think I would be where I am today. I spent six years of Christmases thinking “Next year will be my year.” Now, I look at my daughter and have to pinch myself. I can’t believe she’s here!

My advice to those going through this is to live while you’re waiting. It’s tempting to throw everything you have into the process when you’re going through it. One month off from treatment to take a vacation or celebrate something special is good for your mind and body- don’t forget to nurture yourself.


IVF Family

Patient Story- Molly

IVF Family

“We have been so blessed that I know all the pain and suffering we endured was worth it.”

We’re featuring Molly’s story today! Molly’s story is unique because she was diagnosed with unexplained infertility. This is a tricky diagnosis, because even after testing a cause cannot be determined. When this is the case, there is a lot of trial and error in order to achieve pregnancy. But as Dr. Miller always says: “Trust the process.” That’s just what Molly did and now she has two beautiful sons. Read her story below.

I first became a patient of Dr. Miller’s in 2012 when I had a myomectomy, a surgical procedure to remove uterine fibroids. After getting married and trying for several months to get pregnant, a co-worker suggested I see Dr. Miller, but this time as a fertility specialist. At our first appointment, Dr. Miller ordered blood work and a hysterosonogram which is an ultrasound exam that provides images of the inside of the uterus to help diagnose the cause of abnormal vaginal bleeding. However, everything came back fine. I was told I had unexplained fertility. This wasn’t the news I wanted to hear! It would have been easier to have a specific reason for why I could not get pregnant.

I was put on medication for thyroid and prolactin issues. After a month on the medication, it was advised we try an IUI. We failed all three attempts. Dr. Miller said IVF would need to be our next step. Soon after, my retrieval resulted in 26 eggs! My husband and I were so excited, our dream of having a baby was one step closer.

However, we were unable to do a fresh transfer at that time because I was borderline for Ovarian Hyperstimulation Syndrome (OHSS). This occurs when a woman’s ovaries swell and leak fluid into the body. This condition is temporary and occurs in less than 5% of women who receive fertility treatments. Instead, we ended up freezing 8 embryos. About two months later one embryo was successfully transferred. It was a strange feeling, because I was so happy and terrified at the same time.

After graduating from Dr. Miller’s office, my OB/GYN monitored me closely and that little embryo was born at 34 weeks gestation. Again, I was happy and terrified at the same time. Thankfully our little boy was healthy and strong.

After our son turned 18 months, we decided to start the process to have another child. We decided to follow the same protocol as before and do a transfer in three months. Unfortunately, it failed. After meeting with Dr. Miller again, he advised us to do a trial cycle with an Endometrial Biopsy (EMB). An EMB tests whether the uterine lining is preparing itself adequately for implantation of the embryo. If the lining is out of phase, it can prevent implantation from occurring or result in an early miscarriage. Because the results of my EMB were abnormal, I was treated with progesterone. The following month we had another transfer and it was successful! We welcomed our second baby boy this June./p>

Our two little boys are thriving! We are so happy we found Dr. Miller and are so grateful for everyone in the office as well as Dr. Deutch who did our last transfer. Our advice to other couples going through infertility is to know that you are strong, brave and deserve to be parents. Don’t ever give up! We have been so blessed that I know all the pain and suffering we endured was worth it.

 


Her Own View: A Patient’s Journey Through IVF (Day 26)- Final Preparations and Waiting for Transfer Day

As you might recall from my last post, I had 30 eggs collected, and 10 made it to Preimplantation Genetic Screening (PGS). Out of those 10, five were considered genetically normal. They do know the genders of the normal embryos, but we’ve decided we don’t want to know. We have asked for the best quality embryo to be implanted during our Frozen Embryo Transfer (FET). To be honest, I’m a little surprised that we only had five come back genetically viable. As a 31-year-old, I expected a greater ratio to come back normal. Don’t get me wrong, I’m very, very grateful for having five healthy embryos. I’m also glad I did the test to up my chances of a successful pregnancy.  Dr. Miller says that even in your 20s and 30s, a large percentage of eggs are genetically abnormal.  Add to this, the fact that sperm can also be abnormal, it is not surprising that only 50% of the embryos were tested to be normal.  He said to have five embryos tested and healthy is really very good.

This week, I went in for my FET consultation where they went over my schedule in detail. An FET is great because I now have a pretty solidified schedule for the next month and a half, so I can plan my life. The schedule was based on my ovulation, but unfortunately, I did not ovulate naturally this cycle yet. This happens sometimes because of all the stimulants in my system from my retrieval and hormones can sometimes throw off your cycle. Because of this, I was instructed to inject 3ml of Progesterone in Oil (PIO) intramuscularly to induce my period. I should have my period in the next 7-10 days and they will be able to better control my cycle once that happens. I found the PIO shot to not be as bad as people made it out to be, but again, this was my first one! I used a heating pad before/ after and massaged the contents of the shot into my bum. I was also instructed to start my Lupron injections on Friday.

FET Schedule
FET Schedule

After that, I start taking Estrace which helps build the lining to allow a successful implantation,  Progesterone to help nourish the lining to maintain implantation and a few other things in preparation for my FET on August 28th! I do have to go in for a few more blood/ultrasound tests in the next week, but transfer day is coming up fast! I’m a little nervous that I won’t get my period, which could delay things, but it’s completely out of my hands! I’m just going to focus on self-care for the next month, and make sure I’m doing everything I can to keep myself healthy and happy!

-Katie


Believe

Her Own View: A Patient’s Journey Through IVF (Day 12-25) Adventures in Egg Retrieval

Hi everyone!

I’ve had loads of activity since the last time I updated! Since my last post, I had a third and fourth ultrasound, an egg retrieval and had my embryos shipped to the lab for genetic testing! Yes, a lot can happen in just a few days! Let me break it down…

During my third ultrasound, they saw 12 follicles in my left ovary and 14 follicles in my right ovary. I’ve included a picture so you can see they were still small that day. The size is in the “mean d mm” column. For a follicle to be considered mature, they must be between 16-22mm.

Follicle measurements
Follicle measurements

Dr. Miller requested I come back the next day after he increased my Menopur and Follistim to see if I was ready to pull the Human Chorionic Gonadotropin (HCG) trigger. The HCG trigger shot gives your follicles one last push before the egg retrieval. The shot happens exactly 35 hours before the retrieval. The next day, I had an ultrasound, and I was ready to pull the trigger at exactly 8:30 PM because I was scheduled for my egg retrieval 35 hours later at 7:30 AM. The shots during this time period were not too bad, but by the end, I was very bloated, which is a normal side effect of the medications. Yoga pants, loose tops and layers were my wardrobe staples!

Ultrasound images
Ultrasound images

So here we are, the day of the retrieval! I had to be at the office at 7 AM, for my 7:30 AM egg retrieval procedure. The staff took me in at exactly 7 AM, where they had me change into a hospital gown and gave me discharge instructions. The Anesthetist then hooked up what she needed to, and told me what to expect. The Embryologist also came in and went over the plan (egg retrieval/ freezing embryos, and Preimplantation Genetic Screening (PGS). She mentioned that there would be one update the next day, and we would not get another update until 5 days after that. The staff then took me into the procedure room where I was injected with the anesthesia. The next thing I knew, I was up and with Dan! I think the actual procedure only took 15 minutes. The first thing I heard was, “they got 30 eggs!” The staff was extremely attentive during recovery (about an hour) and Dr. Miller paid me a visit and said he was very pleased with the retrieval.  After the procedure, I took it very easy and napped the rest of the day. I did take a drive with Dan that night to run an errand, which did not go well. I threw up when I got home, probably from the anesthesia and motion sickness from the car! And that is why it’s important to have a driver the day of the retrieval! The procedure was on a Sunday, and I managed to go to work on Monday, although I had to leave early.  I felt uncomfortable for the next few days, but that is a normal side effect.

The next day, I received a call saying, out of the 30 eggs, 26 were mature, and 22 fertilized with ICSI (Intracytoplasmic Sperm Injection). Since I had so many eggs, Dr. Miller put me on a few medications to minimize the risk of Ovarian Hyperstimulation Syndrome (OHSS).

Often times once the retrieval takes place a transfer can be done on Day 3 or Day 5 after the embryos have matured under the care of the embryologist. This is called a fresh cycle because the embryos are “fresh out of the oven.”

However, because we chose to do the PGS testing our transfer turnaround time is a little longer. On Day 5, the lab was happy to report that I had 10 normally developed embryos that could go on to be tested for genetic normalcy.  Those results should be back any day and we will then know how many viable embryos we have. After that, we will also be going through a frozen cycle. This means the embryo(s) will be thawed and then placed into their new home (aka my uterus).

To be honest, I’m enjoying this time where everything is basically out of my control. Let’s see what happens. Stay tuned!

-Katie


pills and medication

Her Own View: A Patient's Journey Through IVF (Days 4-11) Shots, Shots and More Shots

 

I have a few things to update. I started ovarian stimulation and had my first two monitoring appointments. The first appointment was 6 days ago and they took an ultrasound of the uterus to see what’s going on in there. They saw about 18 follicles on that first ultrasound, so they decided to start me on the Menopur (two vials), Follistim (150 units), Lovenox (one pre-filled injection) in addition to the Lupron. Yes, my friends, that’s four shots that I’m injecting into my belly every day! Some women want their husbands to do it, but I decided I wanted to do it myself. I think the mental aspect of taking four shots a day is a lot, and if you must coordinate with your husband to do these shots two times a day, it really adds another layer of complication--so, I stick myself! It’s kind of empowering, believe it or not!

Ok, the shots are NOT BAD! For the Menopur, I have to mix two vials of powder and one ML of solution. There are loads of tutorials on how to do this, so it’s not hard at all. This one does burn a little, but again, not too bad! Follistim is a pen, no mixing with this one. Burns a little, but again, it’s not bad. The Lovenox is by far the worst one. It burns going in. The first time I injected this one, it was PAINFUL! But, since that first injection, my expectations were set and I knew it was going to hurt. And now I’m used to it. If you make it this huge deal, then yes, it will be a huge deal. If you think of it as just part of your day, it’s no big deal. Wash your face, brush your teeth, give yourself your shot….done and done! Move on to the next thing! Also, I’ve not really felt any side effects. I’m bloated, but that could have just been the brownie I ate last night!

My first tiny bruise- this can happen after IVF injections
My first tiny bruise- this can happen after IVF injections

 

On the second ultrasound, they saw over 20 follicles, but all under 10mm. That means they are all small, and they need to keep stimulating me. After the appointment, they increased my Follistim to 300 units from the 150 I was originally on.

 

My first ultrasound and my after ultrasound treat!
My ultrasound and my after ultrasound treat!

 

Dan and I also had to start an antibiotic to reduce the risk of infection at the time of retrieval.  My next appointment is tomorrow, so I will update next week!

Thanks so much for reading!

-Katie

 

*Please note that each patient’s case is unique and Dr. Miller creates individual care plans for each couple based on their medical history.


patient blog

Her Own View: A Patient's Journey Through IVF (Day 1-3)

Today we’re excited to share with you a new blog series about Katie, a patient of Dr. Miller’s, who has experienced difficulty conceiving. She will be sharing her fertility journey with us in her own words. Katie’s goal for journaling her journey, is that you might find comfort and strength in hearing from someone who is also going through the process as well, whether you are going through it now, or are pregnant after months (or years) of trying. Her struggle may be different, but her hopes and dreams of reaching the end goal, that bundle of joy, are the same. Although the outcome is unknown, Dr. Miller and his staff are excited to work together with Katie and her husband, Dan, as their partner and guide.

Hello Everyone!

My name is Katie and I would like to welcome you to my very first patient blog post! I’m excited to take this fertility journey with you. To give you some background, my husband, Dan and I are 31.  After getting married in 2011, both Dan and I went to graduate school, which wasn’t the ideal time to start a family. Finally, at the end of 2015, we were ready to start our family.  We officially started trying to conceive (TTC) in December 2015. To our surprise, we got pregnant the very first month of trying! Unfortunately, in March 2016, we lost the baby at twelve and a half weeks, a few short days after we told close family and friends. Since I had the miscarriage at home, we were not able to test for genetic abnormalities. My OB said over 50% of miscarriages happen because of genetic abnormalities, so that was most likely the reason. The entire experience was truly heartbreaking!

We were told by my OB to wait one cycle before TTC again. Since I had a D&C*, I didn’t get my first period until May 2016. In July 2016, we were pregnant again, which resulted in a chemical pregnancy* at 4.5 weeks. My OB decided to do a Recurrent Pregnancy Loss (RPL)* testing. Those tests indicated that I might have a blood clotting disorder; however, those tests were inconclusive.

My OB suggested we try again since my tests didn’t indicate any real red flags, but to take baby Aspirin for the possible blood clotting issue to be on the safe side. So we did try again, and we were pregnant again in October 2016, which resulted in another chemical pregnancy at 5 weeks. At that time, my OB agreed we should see a Reproductive Endocrinologist (RE).

After performing extensive online research, Dan and I decided to schedule a consultation with Dr. Miller in November 2016.  I chose to see Dr. Miller because of his excellent reputation and success rates.   Before he came in to see Dan and me, Dr. Miller reviewed my case. He said since I have an unknown reason for my recurrent losses, he would like everything tested-- from semen to genetics to blood. You name it, he’s testing it! Since I’m an HMOI patient, and Dr. Miller uses a lab outside the network, the tests had to be done through my OB.

The tests indicated that I have a MTHFR gene mutation*. This mutation does not allow synthetic folic acid to be absorbed into my body, so Dr. Miller gave me a prescription that would allow my body to absorb folic acid. I was hopeful that maybe this could be the answer.

During this time, Dr. Miller also had us do a Clomid* 50mg test cycle to see how my body would respond, but let us know that we would not be TTC just yet. We found that my progesterone was 15 Mg/Ml, lower than the 20 he likes to see with a medicated cycle. Perhaps this was another clue?

In early May 2017, we had our follow up appointment with Dr. Miller, and he talked us through all our options. He said the reasons for my recurrent losses are most likely due to a blood clotting issue or genetic abnormalities. He said we had three options:

  1. Clomid 100mg with Lovenox*
  2. IVF/ICSI* with Lovenox (50% live birth rate/ 16% chance of loss)
  3. IVF/ICSI with Lovenox and Preimplantation Genetic Screening (PGS)*. (70% live birth rate/ less than 5% chance of loss)

We decided to go for option 3! IVF with PGS!

So, here we are! We will do the egg retrieval in June and transfer in July! I’m currently on Lupron * 10 units, which I’ve been taking since May 23rd. Surprisingly, this injection is not bad at all. The needle is tiny and it’s relatively pain-free. I just got my period (finally!), making my cycle 32 days (very long for me as my average in 27 days). I’ll be starting my stimulation shortly here after an ultrasound in the coming days! The plan is to continue the Lupron and add Menopur* and Follistim*. The IVF nurses are really good at keeping me informed on next steps, and I also have a clear written protocol from the office.

I am cautiously excited about the next two months, but I’m not trying to get ahead of myself. I think the most important thing is to take it one step at a time, and not get too into my head about the whole process!

I’ll be updating on my IVF journey a frequently as I have new things to report!

-Katie


Katie's TCC Timeline

  • 2011 – Married! Excited about life together!
  • December 2015 – Removed the goalie! Let’s try to have a baby!
  • March 2016 – 1st miscarriage at twelve and a half weeks. Heartbreaking. Maybe just an unfortunate fluke? Genetic abnormalities? Unknown. D&C to follow.
  • July 2016 – Pregnant again! Chemical pregnancy 4.5 weeks. What’s going on here?
  • August through September 2016 – Recurrent Pregnancy Loss (RPL) testing. Maybe a blood clotting issue?
  • October 2016 – Pregnant again, and you guessed it…another loss at 5 weeks.
  • November 2016 – Started seeing Dr. Miller. Discovered MTHFR gene mutation.
  • March 2017 – Test Clomid cycle. Low progesterone.
  • May 2017 – Starting IVF/ICSI with Lovenox and Preimplantation Genetic Screening (PGS). Taking Lupron 10 units since 5/23/17
  • June 2017 – Got my period, waiting to go in for a baseline ultrasound and starting simulation for the retrieval!

Glossary

D&C: also known as dilation and curettage, a surgical procedure in which the cervix is opened (dilated) and a thin instrument is inserted into the uterus. This instrument is used to remove tissue from the inside of the uterus (curettage).  ACOG

Chemical Pregnancy: occurs when the pregnancy hormone is elevated (i.e. beta hCG), but there are no other signs of pregnancy and it is too early to be detected via ultrasound (ivf.drcharlesmiller.com)

Recurrent Pregnancy Loss (RPL) Testing: examines genetics, infection, autoimmune testing, thrombophilia (blood clotting issues), the structure of the uterus and hormonal concerns (ivf.drcharlesmiller.com)

Clomid:  Clomiphene stimulates the release of hormones needed to cause ovulation. Clomiphene therapy is typically used for 5 consecutive days early in the menstrual cycle, for 3 to 6 monthly cycles. It may take several cycles to find the right dose to stimulate ovulation. After that dose is determined, a woman will take the drug for at least 3 more cycles. If she does not become pregnant after 6 cycles, it is unlikely that further clomiphene treatment will be successful (ivf.drcharlesmiller.com)

Lovenox: Injections used to help prevent micro-clotting associated with Thrombophelia and or auto-immune deficiencies (ivf.drcharlesmiller.com)

IVF/ICSI: refers to a procedure designed to overcome infertility and produce a pregnancy as a direct result of the intervention. In general, the ovaries are stimulated by a combination of fertility medications and then one or more oocyte(s) are aspirated from ovarian follicles. These are fertilized in the laboratory (“in vitro”), after which, one or more embryo(s) are transferred into the uterine cavity. These steps occur over about a two-week interval of time, which is called an IVF cycle. (ivf.drcharlesmiller.com)

Preimplantation Genetic Screening (PGS): performed on cell(s) removed from a preimplantation embryo or a polar body from an oocyte. The goal is to identify de-novo aneuploidy in embryo(s) of couples presumed to be chromosomally normal. Theoretically, avoiding transfer of aneuploid embryos will reduce the risk of pregnancy failure and improve the probability of conceiving a viable pregnancy (ivf.drcharlesmiller.com)

Lupron:  injection given below the skin, subcutaneous injection.  These medications are used to enable the body to produce a higher number of quality eggs. These medications are also designed to prevent the mid-cycle hormonal surge which can result in a cancelled cycle. (ivf.drcharlesmiller.com)

Menopur: (menotropins for injection) is a prescription medicine that contains hormones. MENOPUR contains follicle stimulating hormone and luteinizing hormone activity. These hormones stimulate healthy ovaries to make eggs. (Ferring Pharmaceuticals)

Follistim: medicine that contains follicle-stimulating hormone (FSH) to help healthy ovaries to develop (mature) and release eggs; and as part of treatment programs that use special techniques (skills) to help women get pregnant by causing their ovaries to produce more mature eggs (Merck)

*Please note that each patient's case is unique and Dr. Miller creates individual care plans for each couple based on their medical history. Not all patients who have the MTHFR gene mutation will be treated with Lovenox.